St. Lo (disambiguation)
Saint-Lô is a commune in the Manche department of France.
St. Lo or Saint-Lô may also refer to:
- Laud of Coutances, the bishop after which Saint-Lô was named
 - Saint-Lô station
 - USS St. Lo
 - George St Lo
 - Edward St Lo
 - Alexander St. Lo Malet