List of Mfantsipim School alumni

This is a list of notable alumni of Mfantsipim School.

• Kobina Sekyi - President, Aborigines' Rights Protection Society (ARPS), lawyer, writer, author of The Blinkards
• Kofi Abrefa Busia - Prime Minister of Ghana
• William Ofori Atta - Member of "The Big Six"
• Joseph W.S. de-Graft Johnson - Vice President of Ghana (1979–1981)
• John C. de-Graft Johnson - Ambassador in The Hague (1967–1970)
• Kow Nkensen Arkaah - Vice President of Ghana (1992–1996)
• Kwesi Amissah-Arthur - Vice President of Ghana (2012–2017)
• Albert Adu Boahen - first presidential candidate of the New Patriotic Party (NPP). Flagbearer in the 1992 general election
• Joseph Ephraim Casely-Hayford - lawyer and politician and member of Fante Confederacy and Aborigines' Rights Protection Society
• Papa Owusu-Ankomah - former MP for Sekondi (7 January 1997 – 6 January 2017), and Minister of State (2001–2008).
• Samuel Atta Mills - Member of parliament for the Komenda-Edina-Eguafo-Abirem Constituency (2017–)
• Kwabena Agyapong - politician, former General Secretary of the NPP
• Boakye Agyarko - former Minister for Energy, Ghana
• George Emmanuel Kwesi Aikins - former Attorney General of Ghana
• Kwabena Kwakye Anti - Minister in the second republic
• Joe Appiah - politician
• Albert Bosomtwi-Sam - MP for Sekondi (1992 to 1996)
• Francis Yao Asare - Minister in the first republic
• Kwaku Boateng - minister in the first republic
• T. D. Brodie-Mends - minister in the second republic
• Archie Casely-Hayford - lawyer and politician
• Isaac Chinebuah - academic and politician
• Alexander Apeatu Aboagye da Costa - deputy minister in the Busia government
• Alfred Jonas Dowuona-Hammond - Minister in the first republic
• Kwaku Baah - Deputy Minister in the Busia government
• Kwamena Bartels - Minister of state in the Kufuor government
• Justice Akuamoa Boateng - deputy minister in the Busia government
• Kwamena Duncan - Central Regional Minister, Akufo-Addo government
• John Kofi Fynn - Deputy Minister in the Busia government
• Ashford Emmanuel Inkumsah - minister in the first republic
• J. Kwesi Lamptey - minister in the second republic
• Kofi Asante Ofori-Atta - politician, former Speaker of the Parliament of Ghana
• J. V. L. Phillips - Minister in the NLC regime
• Augustus Obuadum Tanoh - founding member of the National Democratic Congress, founder of the National Reform Party and presidential candidate in the 2000 Ghanaian general election
• Emmanuel Gyekye Tanoh - Minister of state in the PNDC regime
• Samuel Atta Mills - Member of Parliament for Komenda Edina Eguafo Abrem from 2016 to present

• Nana Kobina Nketsia V - Paramount Chief of Essikado Traditional Area

• Joe Ghartey - lawyer, MP for Ketan-Essikado, Minister of Railways
• Edwin Nii Lante Vanderpuye - journalist, MP for Odododiodio
• Anthony Seibu Alec Abban - MP for Ajumako-Asikuma and later Ajumako during the first republic
• Swinthin Maxwell Arko - MP for Agona Nsaba during the first republic
• Dr. Henry Satorius Bannerman - MP for Ashiedu Keteke during the second republic
• Kwabena Okyere Darko-Mensah - MP for Takoradi, Deputy minister
• Kobina Hagan - MP for Denkyira during the first republic
• James Gyakye Quayson - MP for Assin North (elected in 2020 and re-elected in 2023 through a bye-election)
• Samuel Atta Mills - Member of Parliament for Komenda Edina Eguafo Abrem KEEA

• Kofi Annan - former UN Secretary General
• Mohamed Ibn Chambas - former MP and diplomat
• J. L. S. Abbey - former diplomat
• James Aggrey-Orleans - former Ghanaian envoy to the UK
• Francis Lodowic Bartels - former diplomat
• Ebenezer Moses Debrah - former diplomat
• Patrick R. D. Hayford - former diplomat, Ghana's Ambassador to South Africa (1997–1999)
• Alex Quaison-Sackey - first black president of the UN General Assembly
• Nana Effah-Apenteng - former permanent representative of Ghana to the United Nations
• William George Mensah Brandful - retired diplomat
• Papa Owusu-Ankomah, diplomat, 2017 to date
• Miguel Augustus Francisco Ribeiro - former diplomat
• Eric Kwamina Otoo, former diplomat
• Yaw Bamful Turkson, career diplomat and Ambassador(1957-1988)
• Nini Olufemi Akilaja Akiwumi,UN International Civil Servant (UNHCR - High Commissioner's Representative to Russia, Sudan, Papua New Guinea and Sierra Leone) and Ghana's Ambassador Plenipotentiary to Egypt, Lebanon, Cyprus and Sudan 2004 to 2008.

• John Henry Martey Newman - Chief of staff of John Evans Atta Mills administration
• Benjamin Asante - CEO, Ghana National Gas Company

• James Emman Kwegyir Aggrey - Co-Founder of Achimota School
• R. P. Baffour - first Vice Chancellor of KNUST
• Kwame Bediako - first Rector of the Akrofi-Christaller Institute
• Kwasi Kwarfo Adarkwa - former Vice Chancellor of KNUST
• Daniel Afedzi Akyeampong - Ghanaian mathematician pioneer
• Joseph Wilfred Abruquah - novelist, former headmaster of Mfantsipim School and Keta Senior High Technical School
• Samuel Otu Gyandoh - Emeritus Professor of Law
• Kwame Gyekye -Philosopher
• Ato Sekyi-Otu - Academic, Writer, Political philosopher

• Ernest Addison - current Governor of the Bank of Ghana
• Kwesi Amissah-Arthur - former Governor of Bank of Ghana
• G. K. Agama - former Governor of Bank of Ghana

• Emmanuel Akwei Addo – Former Judge of the Court of Appeal; former member of International Law Commission of the United Nations
• George Emmanuel Kwesi Aikins – former Justice of the Supreme Court of Ghana^[1] and Attorney General of Ghana
• Kwadwo Agyei Agyapong – one of the three High Court judges that were abducted and murdered on June 30, 1982.
• Isaac K. Amuah – Justice of the Supreme Court of Ghana (1995–1997)
• Ebo Barton-Odro – MP for Cape Coast (2008-2016), Deputy Attorney-General, and First Deputy Speaker of the Parliament of Ghana
• Kobina Arku Korsah – first Ghanaian Chief Justice of Ghana
• Edmund Alexander Lanquaye Bannerman – 4th Chief Justice of Ghana
• Isaac Kobina Abban – 9th Chief Justice of Ghana and former Chief Justice of Seychelles
• Benjamin Teiko Aryeetey – Justice of the Supreme Court of Ghana (2009–2011)
• Theodore Kwami Adzoe – Justice of the Supreme Court of Ghana (2000–2008)
• William Bruce-Lyle – Supreme Court Judge of Ghana and Zambia
• John Mensah Sarbah – lawyer and academic
• Kurankyi-Taylor
• Joe Ghartey – former Attorney General of Ghana
• J. E. Casely Hayford – lawyer and academician
• William Bedford Van Lare – former justice of the Supreme Court of Ghana
• Samuel Okai Quashie-Idun – former puisne judge of the Supreme Court of Ghana, former Chief Justice of the High Court of Western Nigeria and former President of the Court of Appeal for Eastern Africa
• Papa Owusu-Ankomah – Attorney General of Ghana (2003–2004)
• Emmanuel Gyekye Tanoh – Attorney General of Ghana (1988–1993)
• Tsatsu Tsikata – lawyer and academic
• Isaac Wuaku – retired justice of the Supreme Court of Ghana

• Matthew Quashie - former Chief of Defence Staff of the Ghana Armed Forces
• Erasmus Ransford Tawiah Madjitey - first Ghanaian Commissioner of the Ghana Police Service

• Oku Ampofo - medical practitioner and sculptor
• Raphael Armattoe - medical researcher
• Henry Satorius Bannerman - Formerly president of the Ghana Medical Association and the Commonwealth Medical Association
• David Ofori-Adjei - professor of Clinical Pharmacology
• Harold H. Phillips - formerly Dean of the University of Ghana Medical School

• Berifi Afari Apenteng - Director General of the Ghana Broadcasting Corporation (2011–2013)
• Anis Haffar - educationist, teacher, columnist and author
• Edwin Nii Lante Vanderpuye - journalist, MP for Ododiodio, former Minister of Sports

• Kofi Amoa-Abban - Founder of Rigworld
• Herman Chinery-Hesse - Founder of SOFTtribe, the largest software company in Ghana
• Isaac Sesi - Entrepreneur, Engineer, and Founder of Sesi Technologies
• Edward Annan - Co-owner and Co-founder of Ghanaian domestic airline, Passion Air and Founder of Masai Motors Limited
• Kwasi Twum - Owner and CEO of The Multimedia Group, Ghana's largest independent commercial media group

• Van Vicker - actor
• Kofi Owusu Dua-Anto (KODA) - Gospel Musician
• Majid Michel - actor
• Michael Dei-Anang - playwright, poet and novelist
• Kweku Elliot - actor
• Nii Kwate Owoo - filmmaker
• Joe de Graft - playwright
• Brew Riverson Jnr - actor
• Aaron Adatsi - actor
• (Joseph Pharez Essuman Mensah,RJZ of La meme gang )_ Hip-pop artist, Musician
• Bice Osei Kuffour (Obour)~ Hiplife Musician, Politician

• Kwame Bediako - Christian theologian
• Michael A. Bossman
• Kwesi Dickson

• Derek Boateng - former black stars player
• Arthur Wharton- first black professional footballer in the world
• Kweku Eyiah - lawyer and football administrator
• Aziz Zakari - former Ghana sprinter
• Aziz Mohammed ~ Ghanaian athlete, sprinter
• Samuel Owusu~ Basketball player who merges the MVP at Spriteball 2019 and 2024 Africa Basketball festival.
• Nana Yaw Amponsah Chairman of Asante Kotoko football club

• Mfantsipim Old Boys Association, an organization comprising alumni of Mfantsipim School