HP1
HP1 or variant, may refer to:
- Heterochromatin Protein 1, an important marker molecule in epigenetic research
 - The postal code for part of Hemel Hempstead in Dacorum, see HP postcode area
 - hP1, a Pearson symbol
 - Harry Potter and the Philosopher's Stone, the first novel in J.K. Rowling's Harry Potter series
 - Harry Potter and the Philosopher's Stone (film), the first film in J.K. Rowling's Harry Potter series
 - Handley Page Type A aka H.P.1, an airplane
 - HP-1, a glider designed by Richard Schreder
 - HP1, a type of photographic stock, see Ilford HP
 - Haemophilus phage HP1, a virus
 - Hp.1 (proceed), from German railway signalling