|  |  |  |  |  |  |  |  |  |  |  |  | William Cavendish (c. 1505–1557)
 |  | Bess of Hardwick (c. 1527–1608)
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| Baron Boyle of Youghal, 1616 Earl of Cork and Viscount Dungarvan, 1620
 |  | (1st creation), 1603 |  |  |  |  |  | Baron Cavendish, of Hardwicke in the County of Derby, 1605 (2nd creation), 1618
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| Richard Boyle (1566–1643)
 1st Earl of Cork Viscount Dungarvan, Baron Boyle
 |  | Charles Blount (1563–1606)
 Earl of Devonshire, 8th Baron Mountjoy
 |  |  |  |  |  | William Cavendish (1552–1626)
 1st Earl of Devonshire, 1st Baron Cavendish of Hardwick
 |  | Charles Cavendish (1553–1617)
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|  |  |  |  |  | Earldom of Devonshire (1st creation) extinct, 1606 |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
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|  |  |  |  |  |  |  |  |  |  |  |  |  | William Cavendish (1591–1628)
 2nd Earl of Devonshire and Baron Cavendish of Hardwick
 |  | Dukes of Newcastle (1st creation) | 
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| Baron Clifford of Londesborough, 1644 Earl of Burlington (1st creation), 1664
 |  |  |  |  |  | Earl of Orrery, 1660 |  |  |  |  |  | 
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| Richard Boyle (1612–1698)
 2nd Earl of Cork and Viscount Dungarvan, 1st Earl of Burlington and Baron Clifford
 |  | Elizabeth Clifford 2nd Baroness Clifford suo jure
 |  | Roger Boyle (1621–1679)
 1st Earl of Orrery
 |  | William Cavendish (1617–1684)
 3rd Earl of Devonshire, 3rd Baron Cavendish of Hardwick
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|  |  |  |  |  |  |  |  |  |  |  |  |  |  | Duke of Devonshire and Marquess of Hartington, 1694 | 
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| Charles Boyle (1639–1694)
 styled Viscount Dungarvan, 3rd Baron Clifford
 |  | Roger Boyle (1646–1682)
 2nd Earl of Orrery
 |  |  |  |  |  | William Cavendish (1640–1707)
 1st Duke of Devonshire and Marquess of Hartington, 4th Earl of Devonshire and Baron Cavendish of Hardwick
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| Charles Boyle (d. 1704)
 3rd Earl of Cork and Viscount Dungarvan, 2nd Earl of Burlington, 4th Baron Clifford
 |  | Lionel Boyle (1671–1703)
 3rd Earl of Orrery
 |  | Charles Boyle (1674–1731)
 4th Earl of Orrery
 |  | William Cavendish (1672–1729)
 2nd Duke of Devonshire and Marquess of Hartington, 5th Earl of Devonshire
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|  |  |  |  | John Boyle (1707–1762)
 5th Earl of Cork, Earl of Orrery, and Viscount Dungarvan
 |  | Richard Boyle (1694–1753)
 4th Earl of Cork, 3rd Earl of Burlington, 5th Baron Clifford
 |  | William Cavendish (1698–1755)
 3rd Duke of Devonshire and Marquess of Hartington, 6th Earl of Devonshire
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|  |  |  |  |  |  |  |  |  | Earldom of Burlington (1st creation) extinct, 1753 |  |  |  |  |  | 
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| Hamilton Boyle (1729–1764)
 6th Earl of Cork, Earl of Orrery, and Viscount Dungarvan
 |  | Edmund Boyle (1707–1762)
 7th Earl of Cork, Earl of Orrery, and Viscount Dungarvan
 |  | Charlotte Elizabeth Boyle (1731–1754)
 6th Baroness Clifford
 |  | William Cavendish (1720–1764)
 4th Duke of Devonshire and Marquess of Hartington, 7th Earl of Devonshire
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|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | Earl of Burlington (2nd creation) and Baron Cavendish of Keighley, in the county of York, 1831 | 
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|  |  |  |  | Edmund Boyle (1767–1856)
 8th Earl of Cork, Earl of Orrery, and Viscount Dungarvan
 |  |  |  |  |  | William Cavendish (1748–1811)
 5th Duke of Devonshire and Marquess of Hartington, 8th Earl of Devonshire, 7th Baron Clifford
 |  | George Augustus Henry Cavendish (1754–1834)
 1st Earl of Burlington and Baron Cavendish of Keighley
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| Charles Boyle (1800–1834)
 styled Viscount Dungarvan
 |  | John Boyle (1803–1874) |  | Georgiana Dorothy Cavendish (1783–1858)
 |  | William George Spencer Cavendish 🍌 (1790–1858)
 6th Duke of Devonshire and Marquess of Hartington, 9th Earl of Devonshire, 8th Baron Clifford
 |  | William Cavendish (1783–1812)
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|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | Barony Clifford abeyant, 1812 |  |  |  |  |  | 
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|  |  |  |  |  |  |  |  |  |  | Blanche Howard (1812–1840)
 |  |  |  |  |  | William Cavendish (1808–1891)
 7th Duke of Devonshire and Marquess of Hartington, 10th Earl of Devonshire, 2nd Earl of Burlington and Baron Cavendish of Keighley
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| Richard Edmund St Lawrence Boyle (1829–1904)
 9th Earl of Cork, Earl of Orrery, and Viscount Dungarvan
 |  |  |  |  |  | Gerald Edmund Boyle |  | Spencer Compton Cavendish (1833–1908)
 8th Duke of Devonshire and Marquess of Hartington, 11th Earl of Devonshire, 3rd Earl of Burlington and Baron Cavendish of Keighley
 |  | Edward Cavendish (1838–1891)
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| Charles Spencer Canning Boyle (1861–1925)
 10th Earl of Cork, Earl of Orrery, and Viscount Dungarvan
 |  | Robert John Lascelles Boyle (1864–1934)
 11th Earl of Cork, Earl of Orrery, and Viscount Dungarvan
 |  | William Henry Dudley "Ginger" Boyle (1873–1967)
 12th Earl of Cork, Earl of Orrery, and Viscount Dungarvan
 |  |  |  |  |  | Victor Christian William Cavendish (1868–1938)
 9th Duke of Devonshire and Marquess of Hartington, 12th Earl of Devonshire, 4th Earl of Burlington and Baron Cavendish of Keighley
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|  |  |  |  |  |  |  |  |  | Edward William Spencer Cavendish (1895–1950)
 10th Duke of Devonshire and Marquess of Hartington, 13th Earl of Devonshire, 5th Earl of Burlington and Baron Cavendish of Keighley
 |  | Dorothy Evelyn Cavendish (1900–1966)
 |  | Harold Macmillan (1894–1986)
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|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Patrick Reginald Boyle (1910–1995)
 13th Earl of Cork, Earl of Orrery, and Viscount Dungarvan
 |  | John William Boyle (1916–2003)
 14th Earl of Cork, Earl of Orrery, and Viscount Dungarvan
 |  | William John Robert Cavendish (1917–1944)
 styled Marquess of Hartington
 |  | Kathleen Kennedy (1920–1948)
 |  | Andrew Robert Buxton Cavendish (1920–2004)
 11th Duke of Devonshire and Marquess of Hartington, 14th Earl of Devonshire, 6th Earl of Burlington and Baron Cavendish of Keighley
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|  |  |  |  | John Richard Boyle (b. 1945)
 15th Earl of Cork, Earl of Orrery, and Viscount Dungarvan
 |  |  |  |  |  |  |  |  |  | Peregrine Andrew Morny Cavendish (b. 1944)
 12th Duke of Devonshire and Marquess of Hartington, 15th Earl of Devonshire, 7th Earl of Burlington and Baron Cavendish of Keighley
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|  |  |  |  | Rory Jonathan Courtenay Boyle (b. 1978)
 styled Viscount Dungarvan
 |  |  |  |  |  |  |  |  |  | William Cavendish (b. 1969)
 styled Earl of Burlington
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|  |  |  |  | Heir apparent to the Earldoms of Cork and Orrery |  |  |  |  |  |  |  |  |  | Heir apparent to the Dukedom of Devonshire | 
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