2022 US Open – Wheelchair men's doubles
| Wheelchair men's doubles | |
|---|---|
| 2022 US Open | |
| Champions | |
| Runners-up | |
| Score | 4–6, 7–5, [10–6] | 
Martín de la Puente and Nicolas Peifer defeated the five-time defending champions Alfie Hewett and Gordon Reid[1] in the final, 4–6, 7–5, [10–6] to win the men's doubles wheelchair tennis title at the 2022 US Open. It was de la Puente's maiden major title, and Peifer's eighth in doubles.
Seeds
 Alfie Hewett / 
 Gordon Reid (final)
 Martín de la Puente / 
 Nicolas Peifer (champions)
Draw
Key
- Q = Qualifier
 - WC = Wild card
 - LL = Lucky loser
 - Alt = Alternate
 - ITF = ITF entry
 - PR = Protected ranking
 - SR = Special ranking
 - SE = Special exempt
 - JE = Junior exempt
 - JR = Junior Accelerator Programme entrant
 - CO = College Accelerator Programme entrant
 - NG = Next Gen Accelerator Program entrant
 - w/o = Walkover
 - r = Retired
 - d = Defaulted
 
Finals
| Quarterfinals | Semifinals | Final | ||||||||||||||||||
| 1 | w/o | |||||||||||||||||||
| 1 | 6 | 6 | ||||||||||||||||||
| 3 | 3 | |||||||||||||||||||
| 6 | 3 | [4] | ||||||||||||||||||
| 2 | 6 | [10] | ||||||||||||||||||
| 1 | 6 | 5 | [6] | |||||||||||||||||
| 2 | 4 | 7 | [10] | |||||||||||||||||
| 7 | 6 | |||||||||||||||||||
| 5 | 4 | |||||||||||||||||||
| 3 | 6 | [6] | ||||||||||||||||||
| 2 | 6 | 4 | [10] | |||||||||||||||||
| 4 | 0 | |||||||||||||||||||
| 2 | 6 | 6 | ||||||||||||||||||