2021 Karlsruhe Open – Singles

Singles
2021 Karlsruhe Open
Champion	Mayar Sherif
Runner-up	Martina Trevisan
Score	6–3, 6–2

The 2021 Karlsruhe Open (also known as the Liqui Moly Open for sponsorship reasons) was a professional tennis tournament played on outdoor clay courts. It was the 2nd edition of the tournament and part of the 2021 WTA 125K series, offering a total of $125,000 in prize money. It took place in Karlsruhe, Germany between 7 and 12 September 2021. The tournament did not take place in 2020 due to the COVID-19 pandemic.^[1] The singles part of the tournament had 32 competitors. Patricia Maria Țig was the defending champion, having won the previous edition in 2019,^[2] but chose not to participate. Mayar Sherif won the title, defeating Martina Trevisan in the final, 6–3, 6–2.

	Semifinals							Final
		Jaqueline Cristian	63	6	4
	3	Mayar Sherif	77	4	6
								3	Mayar Sherif	6	6
								4	Martina Trevisan	3	2
	4	Martina Trevisan	6	4	6
	6	Maryna Zanevska	3	6	4

	First round							Second round							Quarterfinals							Semifinals
	1	C Burel	79	3	2
		J Cristian	67	6	6			J Cristian		6	77
		L Bronzetti	6	3	6			L Bronzetti		1	62
		RL Jani	4	6	1											J Cristian	6	6
	WC	N Schunk	6	3	7										WC	N Schunk	1	1
	Q	K Hobgarski	0	6	5			WC	N Schunk	6	6
	Q	Y Morderger	1	2				7	A Sharma	2	4
	7	A Sharma	6	6																			J Cristian	63	6	4
	3	M Sherif	6	6																		3	M Sherif	77	4	6
	WC	S Herrmann	0	2				3	M Sherif	6	6
		M Inglis	1r						K Kawa	3	4
		K Kawa	2												3	M Sherif	6	6
	WC	T Maria	7	2	4											R Šramková	3	2
		K Zavatska	5	6	6			K Zavatska		7	2	4
		R Šramková	6	6				R Šramková		5	6	6
	5	K Juvan	4	1

	First round							Second round							Quarterfinals							Semifinals
	8	I Bara	3	6	6
		P Ormaechea	6	4	3			8	I Bara	4	3
		E Gorgodze	4	66					D Gálfi	6	6
		D Gálfi	6	78												D Gálfi	62	5
		G Min	6	6											4	M Trevisan	77	7
	Q	G Gatto-Monticone	0	2					G Min	1	63
		A Gasanova	64	3				4	M Trevisan	6	77
	4	M Trevisan	77	6																		4	M Trevisan	6	4	6
	6	M Zanevska	5	6	6																	6	M Zanevska	3	6	4
		C Bucșa	7	4	2			6	M Zanevska	6	6
		T Korpatsch	2	66				Q	T Mrdeža	1	2
	Q	T Mrdeža	6	78											6	M Zanevska	1	6	6
		M Fręch	6	6												A Bondár	6	4	4
	WC	A Vecic	2	2				M Fręch		3	3
		A Bondár	6	63	7			A Bondár		6	6
	2	AK Schmiedlová	2	77	5

	Qualifying competition
	1	Giulia Gatto-Monticone	1	6	6
		Anna Zaja	6	4	3

	Qualifying competition
	2	Mona Barthel	0	6	2
		Yana Morderger	6	3	6

	Qualifying competition
	3	Tereza Mrdeža	6	6
	WC	Eva Lys	0	3

	Qualifying competition
	4	Katharina Hobgarski	6	6
	WC	Joëlle Steur	3	2

• Main Draw
• Qualifying Draw