2010 Western & Southern Financial Group Women's Open – Singles

Singles
2010 Western & Southern Financial Group Women's Open
Champion	Kim Clijsters
Runner-up	Maria Sharapova
Score	2–6, 7–6(7–4), 6–2
Draw	56
Seeds	16

Kim Clijsters defeated Maria Sharapova in the final, 2–6, 7–6^(7–4), 6–2 to win the women's singles tennis title at the 2010 Cincinnati Masters. She saved three championship points en route to the title. It was Sharapova's second final defeat in as many weeks, having lost the Stanford final to Victoria Azarenka just two weeks earlier.

Jelena Janković was the defending champion, but lost in the third round to Akgul Amanmuradova.

Ana Ivanovic, ranked as the world No. 62 entering the tournament, upset Azarenka in the first round, having trailed 2–6, 2–5 before fighting back to win the match, 2–6, 7–6^(8–6), 6–2.^[1] She then went on to make her third semifinal of the year, being forced to retire against Clijsters after injuring her foot.^[2]

The top eight seeds receive a bye into the second round.

	Quarterfinals							Semifinals							Final
	Q	Akgul Amanmuradova	1	3
		Ana Ivanovic	6	6
									Ana Ivanovic	1r
								4	Kim Clijsters	2
	4	Kim Clijsters	78	6
	11	Flavia Pennetta	66	4
															4	Kim Clijsters	2	77	6
															10	Maria Sharapova	6	64	2
	12	Yanina Wickmayer	5	6	1
		Anastasia Pavlyuchenkova	7	3	6
									Anastasia Pavlyuchenkova	4	6	2
								10	Maria Sharapova	6	3	6
	10	Maria Sharapova	6	6
	16	Marion Bartoli	1	4

	First round							Second round							Third round							Quarterfinals
								1	J Janković	6	3	6
	Q	V Dushevina	6	7				Q	V Dushevina	4	6	1
	Q	A Rodionova	2	67											1	J Janković	63	4
	Q	K Date-Krumm	1	2											Q	A Amanmuradova	7	6
	Q	A Amanmuradova	6	6				Q	A Amanmuradova	6	6
	Q	B Jovanovski	4	6	6			Q	B Jovanovski	2	0
	14	A Rezaï	6	3	4																	Q	A Amanmuradova	1	3
	9	V Azarenka	6	66	2																		A Ivanovic	6	6
		A Ivanovic	2	7	6				A Ivanovic	6	7
		Y Shvedova	7	6					Y Shvedova	1	5
	Q	A Kudryavtseva	5	4												A Ivanovic	6	6
		E Vesnina	6	6												E Vesnina	0	3
		M Oudin	2	3					E Vesnina	6	6
								5	F Schiavone	4	4

	First round							Second round							Third round							Quarterfinals
								4	K Clijsters	7	6
		D Safina	7	6					D Safina	5	2
		R Vinci	5	4											4	K Clijsters	6	6
	Q	A Morita	7	6											WC	C McHale	1	1
		A Parra Santonja	67	2				Q	A Morita	2	4
	WC	C McHale	7	5				WC	C McHale	6	6
	15	N Petrova	64	3	r																	4	K Clijsters	7	6
	11	F Pennetta	6	6																		11	F Pennetta	66	4
		J Zheng	4	2				11	F Pennetta	6	6
	Q	M Niculescu	6	6				Q	M Niculescu	0	1
		S Lisicki	3	0											11	F Pennetta	6	6
		M Kirilenko	6	6											6	V Zvonareva	4	3
		K Bondarenko	1	3					M Kirilenko	5	6	62
								6	V Zvonareva	7	2	7

	First round							Second round							Third round							Quarterfinals
								8	N Li	6	6
	WC	J Hampton	4	2					S Errani	2	2
		S Errani	6	6											8	N Li	6	2	64
		G Dulko	6	6											12	Y Wickmayer	2	6	7
		L Šafářová	4	3					G Dulko	63	2
	Q	G Arn	2	2				12	Y Wickmayer	7	6
	12	Y Wickmayer	6	6																		12	Y Wickmayer	5	6	1
	13	S Pe'er	6	4																			A Pavlyuchenkova	7	3	6
		O Govortsova	3	1	r			13	S Pe'er	6	6
	Q	V King	6	3	1			Q	N Llagostera Vives	3	2
	Q	N Llagostera Vives	3	6	6										13	S Pe'er	7	4	4
		D Hantuchová	3	4												A Pavlyuchenkova	5	6	6
		A Pavlyuchenkova	6	6					A Pavlyuchenkova	6	6
								3	E Dementieva	1	3

	First round							Second round							Third round							Quarterfinals
								7	A Radwańska	6	6
		A Kleybanova	6	6					A Kleybanova	4	2
		A Dulgheru	4	4											7	A Radwańska	2	3
		A Petkovic	7	6											10	M Sharapova	6	6
	WC	C Vandeweghe	61	1					A Petkovic	3	1
		S Kuznetsova	4	6	2			10	M Sharapova	6	6
	10	M Sharapova	6	1	6																	10	M Sharapova	6	6
	16	M Bartoli	6	6																		16	M Bartoli	1	4
		A Medina Garrigues	4	0				16	M Bartoli	7	6
		D Cibulková	6	2	3				A Bondarenko	64	1
		A Bondarenko	3	6	6										16	M Bartoli	6	6
		S Bammer	7	6											2	C Wozniacki	4	1
	Q	S Cîrstea	65	2					S Bammer	0	2
								2	C Wozniacki	6	6

• Main Draw
• Qualifying Draw